Experimental and Theoretical Studies on Formability of 22MnB5 at Elevated Temperatures by Gleeble Simulator

AbstractThis paper, which includes an experimental analysis and theoretical predictions, presents a method to investigate the formability of high strength steel sheet 22MnB5 at elevated temperatures. In this method, two designs for tensile test specimens with laser engraving grids are developed and used to obtain the strain paths of a uniaxial tensile state and the plane strain occurring at elevated temperatures using a Gleeble simulator. On the other hand, a modified Cockcroft criterion that takes strain path into consideration is employed to predict the entire forming limit diagram. A forming limit diagram could be established as a result of using the modified Cockcroft criterion together with the limit strains obtained from the tensile tests based on two novel specimen designs. In this paper, forming limit diagrams at three strain rates and forming limit diagrams at temperatures ranging from 650 oC to 850 oC were established

Nonparetic Knee Extensor Strength Is the Determinant of Exercise Capacity of Community-Dwelling Stroke Survivors

Objective. To investigate the relationship among walking speed, exercise capacity, and leg strength in community dwelling stroke subjects and to evaluate which one was the leading determinant factor of them. Design. This is a descriptive, cross-sectional study. Thirty-five chronic stroke patients who were able to walk independently in their community were enrolled. Walking speed was evaluated by using the 12-meter walking test. A maximal exercise test was used to determine the stroke subjects’ exercise capacity. Knee extensor strength, measured as isokinetic torque, was assessed by isokinetic dynamometer. Results. The main walking speed of our subjects was 0.52 m/s. Peak oxygen uptake (VO2 peak) was 1.21±0.43 L/min. Knee extensor strength, no matter whether paretic or nonparetic side, was significantly correlated to 12-meter walking speed and exercise capacity. Linear regression also showed the strength of the affected knee extensor was the determinant of walking speed and that of the nonparetic knee extensor was the determinant of exercise capacity in community dwelling stroke subjects. Conclusions. Walking speed and peak oxygen uptake were markedly decreased after stroke. Knee extensor strength of nonparetic leg was the most important determinant of exercise capacity of the community-dwelling stroke subjects. Knee extensor strengthening should be emphasized to help stroke patient to achieve optimal community living

Synchronous Occurrence of Primary Neoplasms in the Uterus with Squamous Cell Carcinoma of the Cervix and Adenocarcinoma of the Endometrium

SummaryObjectiveSynchronous primary malignant neoplasms of the uterus are uncommon. Patients with synchronous cervical and endometrial cancers are even rarer. We describe a case of cervical squamous cell carcinoma and endometrial endometrioid adenocarcinoma occurring simultaneously in a 47-year-old woman presenting with massive menstrual bleeding. The concept of synchronous primary malignancies of the genital tract is also reviewed in this report.Case ReportA 47-year-old overtly obese female presented with menometrorrhagia of over 6 months' duration. Pelvic examination detected a large cervix but apparently normal externals. Magnetic resonance imaging revealed a mass over the cervical region and endometrial lesions in the uterine cavity. Surgical exploration disclosed a cervical tumor and erosion of the endometrium. The pathologic findings were compatible with synchronous occurrence of primary neoplasms in the uterus with squamous cell carcinoma of the cervix and adenocarcinoma of the endometrium.ConclusionSynchronous genital tract neoplasms are rare but cause more clinical problems than a single neoplasm. It is practical to pay more attention to the differential diagnosis of primary and metastatic tumors. The second primary cancer that occurs in an individual with endometrial cancer may offer an opportunity for early detection. The prognosis for a patient with synchronous gynecologic malignancies does not seem to be worse

Supporting Service Management with Service Encounters Analysis: A Case on Call Centre Outsourcing Operations

Background. A service encounter is the moment that a client directly interacts with a service firm. It is a social-oriented activity that an in-depth analysis of how the client behaved can contribute to the service quality. Objective. The primary objective of this study was to cluster the CLT into groups. The secondary objective was to discover the sequence of question types that asked in each group. Method. A real world call centre outsourcing practice and data mining techniques are used to discover client behaviour. Results. A total of 100,703 inbound calls from the call centre operational database are analyzed. 90.4% of the total calls were made by 85% of clients who used up to three business applications. 72.03% of the total calls were made by a group of clients who involved two to five question types. The clients were clustered into four groups by three behaviour variables. The sequences discovered in this study were mainly on two question types. Conclusion. The service encounter is a complex business process that an integrated perspective should be taken to analyze the dynamics among the entities involved. The client behaviour can be discovered and used as the feedback information for turning the operations in different organizational levels

Optical music recognition of the singer using formant frequency estimation of vocal fold vibration and lip motion with interpolated GMM classifiers

The main work of this paper is to identify the musical genres of the singer by performing the optical detection of lip motion. Recently, optical music recognition has attracted much attention. Optical music recognition in this study is a type of automatic techniques in information engineering, which can be used to determine the musical style of the singer. This paper proposes a method for optical music recognition where acoustic formant analysis of both vocal fold vibration and lip motion are employed with interpolated Gaussian mixture model (GMM) estimation to perform musical genre classification of the singer. The developed approach for such classification application is called GMM-Formant. Since humming and voiced speech sounds cause periodic vibrations of the vocal folds and then the corresponding motion of the lip, the proposed GMM-Formant firstly operates to acquire the required formant information. Formant information is important acoustic feature data for recognition classification. The proposed GMM-Formant method then uses linear interpolation for combining GMM likelihood estimates and formant evaluation results appropriately. GMM-Formant will effectively adjust the estimated formant feature evaluation outcomes by referring to certain degree of the likelihood score derived from GMM calculations. The superiority and effectiveness of presented GMM-Formant are demonstrated by a series of experiments on musical genre classification of the singer

Glutamatergic Dysfunction and Glutamatergic Compounds for Major Psychiatric Disorders: Evidence From Clinical Neuroimaging Studies

Excessive glutamate release has been linked to stress and many neurodegenerative diseases. Evidence indicates abnormalities of glutamatergic neurotransmission or glutamatergic dysfunction as playing an important role in the development of many major psychiatric disorders (e.g., schizophrenia, bipolar disorder, and major depressive disorder). Recently, ketamine, an N-methyl-d-aspartate antagonist, has been demonstrated to have promisingly rapid antidepressant efficacy for treatment-resistant depression. Many compounds that target the glutamate system have also become available that possess potential in the treatment of major psychiatric disorders. In this review, we update evidence from recent human studies that directly or indirectly measured glutamatergic neurotransmission and function in major psychiatric disorders using modalities such as magnetic resonance spectroscopy, positron emission tomography/single-photon emission computed tomography, and paired-pulse transcranial magnetic stimulation. The newer generation of antidepressants that target the glutamatergic system developed in human clinical studies is also reviewed